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Histone deacetylase inhibitors and hemoglobin F induction in β-thalassemia
Epigenomic modifiers, such as histone deacetylase inhibitors, are compounds that regulate gene expression by interfering with the enzymatic machinery that maintains the proper chromatin structure of the nucleus. These compounds are at the forefront of novel therapeutic agents for the treatment of se...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581454/ https://ncbi.nlm.nih.gov/pubmed/18617435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2008.04.024 |
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