Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a

Current evidence indicates that methylation of cytosine in mammalian DNA is restricted to both strands of the symmetrical sequence CpG, although there have been sporadic reports that sequences other than CpG may also be methylated. We have used a dual-labeling nearest neighbor technique and bisulphi...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ramsahoye, Bernard H., Biniszkiewicz, Detlev, Lyko, Frank, Clark, Victoria, Bird, Adrian P., Jaenisch, Rudolf
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25812/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10805783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.10.5237
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