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uPA is upregulated by high dose celecoxib in women at increased risk of developing breast cancer

BACKGROUND: While increased urokinase-type plasminogen activator (uPA) expression in breast cancer tissue is directly associated with poor prognosis, recent evidence suggests that uPA overexpression may suppress tumor growth and prolong survival. Celecoxib has been shown to have antiangiogenic and a...

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書誌詳細
主要な著者: Qin, Wenyi, Zhu, Weizhu, Hewett, John E, Rottinghaus, George, Chen, Yin-Chieh, Flynn, John T, Kliethermes, Beth, Mannello, Ferdinando, Sauter, Edward R
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2580770/
https://ncbi.nlm.nih.gov/pubmed/18922176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-298
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