uPA is upregulated by high dose celecoxib in women at increased risk of developing breast cancer

BACKGROUND: While increased urokinase-type plasminogen activator (uPA) expression in breast cancer tissue is directly associated with poor prognosis, recent evidence suggests that uPA overexpression may suppress tumor growth and prolong survival. Celecoxib has been shown to have antiangiogenic and a...

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Detalhes bibliográficos
Main Authors: Qin, Wenyi, Zhu, Weizhu, Hewett, John E, Rottinghaus, George, Chen, Yin-Chieh, Flynn, John T, Kliethermes, Beth, Mannello, Ferdinando, Sauter, Edward R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2580770/
https://ncbi.nlm.nih.gov/pubmed/18922176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-298
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