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Analysis of IgA1 N-glycosylation and its contribution to FcαRI binding
The IgA isotype of human antibodies triggers inflammatory responses via the IgA-specific receptor FcαRI (CD89). Structural studies have suggested that IgA1 N-glycans could modulate the interaction with FcαRI. We have carried out detailed biophysical analyses of three IgA1 samples purified from human...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2580753/ https://ncbi.nlm.nih.gov/pubmed/18826328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801185b |
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