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Chaperonin chamber accelerates protein folding through passive action of preventing aggregation

The original experiments reconstituting GroEL–GroES-mediated protein folding were carried out under “nonpermissive” conditions, where the chaperonin system was absolutely required and substrate proteins could not achieve the native state if diluted directly from denaturant into solution. Under “perm...

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Detalhes bibliográficos
Main Authors: Apetri, Adrian C., Horwich, Arthur L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579888/
https://ncbi.nlm.nih.gov/pubmed/18987317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809794105
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