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Production of a specific extracellular inhibitor of TRPM3 channels

BACKGROUND AND PURPOSE: Isoform-specific ion channel blockers are useful for target validation in drug discovery and can provide the basis for new therapeutic agents and aid in determination of physiological functions of ion channels. The aim of this study was to generate a specific blocker of human...

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Autors principals: Naylor, J, Milligan, C J, Zeng, F, Jones, C, Beech, D J
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579657/
https://ncbi.nlm.nih.gov/pubmed/18604232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.283
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