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5-Methylcytosine-DNA glycosylase activity is present in a cloned G/T mismatch DNA glycosylase associated with the chicken embryo DNA demethylation complex

We previously have shown that DNA demethylation by chicken embryo 5-methylcytosine DNA glycosylase (5-MCDG) needs both RNA and proteins. One of these proteins is a RNA helicase. Further peptides were sequenced, and three of them are identical to the mammalian G/T mismatch DNA glycosylase. A 3,233-bp...

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Autori principali: Zhu, Bing, Zheng, Yong, Hess, Daniel, Angliker, Herbert, Schwarz, Steffen, Siegmann, Michel, Thiry, Stéphane, Jost, Jean-Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC25794/
https://ncbi.nlm.nih.gov/pubmed/10779566
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