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5-Methylcytosine DNA glycosylase activity is also present in the human MBD4 (G/T mismatch glycosylase) and in a related avian sequence

A 1468 bp cDNA coding for the chicken homolog of the human MBD4 G/T mismatch DNA glycosylase was isolated and sequenced. The derived amino acid sequence (416 amino acids) shows 46% identity with the human MBD4 and the conserved catalytic region at the C-terminal end (170 amino acids) has 90% identit...

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Detalhes bibliográficos
Main Authors: Zhu, Bing, Zheng, Yong, Angliker, Herbert, Schwarz, Steffen, Thiry, Stéphane, Siegmann, Michel, Jost, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC113156/
https://ncbi.nlm.nih.gov/pubmed/11058112
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