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Importin-mediated retrograde transport of CREB2 from distal processes to the nucleus in neurons

Signals received at distal synapses of neurons must be conveyed to the nucleus to initiate the changes in transcription that underlie long-lasting synaptic plasticity. The presence of importin nuclear transporters and of select transcription factors at synapses raises the possibility that importins...

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Detalhes bibliográficos
Main Authors: Lai, Kwok-On, Zhao, Yali, Ch'ng, Toh Hean, Martin, Kelsey C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579397/
https://ncbi.nlm.nih.gov/pubmed/18957537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803906105
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