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Microglial activation and TNFα production mediate altered CNS excitability following peripheral inflammation

Peripheral inflammation leads to a number of centrally mediated physiological and behavioral changes. The underlying mechanisms and the signaling pathways involved in these phenomena are not yet well understood. We hypothesized that peripheral inflammation leads to increased neuronal excitability ar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Riazi, Kiarash, Galic, Michael A., Kuzmiski, J. Brent, Ho, Winnie, Sharkey, Keith A., Pittman, Quentin J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579393/
https://ncbi.nlm.nih.gov/pubmed/18955701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806682105
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