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Microglial activation and TNFα production mediate altered CNS excitability following peripheral inflammation

Peripheral inflammation leads to a number of centrally mediated physiological and behavioral changes. The underlying mechanisms and the signaling pathways involved in these phenomena are not yet well understood. We hypothesized that peripheral inflammation leads to increased neuronal excitability ar...

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Detalhes bibliográficos
Main Authors: Riazi, Kiarash, Galic, Michael A., Kuzmiski, J. Brent, Ho, Winnie, Sharkey, Keith A., Pittman, Quentin J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579393/
https://ncbi.nlm.nih.gov/pubmed/18955701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806682105
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