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Crystal structure of Escherichia coli PNPase: Central channel residues are involved in processive RNA degradation
Bacterial polynucleotide phosphorylase (PNPase) plays a major role in mRNA turnover by the degradation of RNA from the 3′- to 5′-ends. Here, we determined the crystal structures of the wild-type and a C-terminal KH/S1 domain-truncated mutant (ΔKH/S1) of Escherichia coli PNPase at resolutions of 2.6...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2578853/ https://ncbi.nlm.nih.gov/pubmed/18812438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1244308 |
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