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Computational models explain the oligosaccharide specificity of cyanovirin-N

The prokaryotic lectin cyanovirin-N (CV-N) is a potent inhibitor of HIV envelope-mediated cell entry, and thus is a leading candidate among a new class of potential anti-HIV microbicides. The activity of CV-N is a result of interactions with the D1 arm of high-mannose oligosaccharides on the viral g...

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Autors principals: Fujimoto, Yukiji K., TerBush, Ryan N., Patsalo, Vadim, Green, David F.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2578810/
https://ncbi.nlm.nih.gov/pubmed/18809850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.034637.108
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