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Molecular pathways of programmed cell death in experimental Parkinson’s disease
Dysfunction of mitochondrial complex I leads to degeneration of dopaminergic neurons of the substantia nigra pars compacta, as seen in Parkinson’s disease, through activation of mitochondria-dependent programmed cell death pathways. In this scenario, complex I blockade increases the soluble pool of...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2577905/ https://ncbi.nlm.nih.gov/pubmed/18595766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parkreldis.2008.04.026 |
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