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Mapping short DNA sequencing reads and calling variants using mapping quality scores

New sequencing technologies promise a new era in the use of DNA sequence. However, some of these technologies produce very short reads, typically of a few tens of base pairs, and to use these reads effectively requires new algorithms and software. In particular, there is a major issue in efficiently...

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Detalhes bibliográficos
Main Authors: Li, Heng, Ruan, Jue, Durbin, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577856/
https://ncbi.nlm.nih.gov/pubmed/18714091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.078212.108
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