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Amyloid-β Dynamics Correlate with Neurological Status in the Injured Human Brain

The amyloid-β peptide (Aβ) plays a central pathophysiological role in Alzheimer’s disease, but little is known about the concentration and dynamics of this secreted peptide in the extracellular space of the human brain. We used intracerebral microdialysis to obtain serial brain interstitial fluid (I...

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Bibliografiske detaljer
Main Authors: Brody, David L., Magnoni, Sandra, Schwetye, Kate E., Spinner, Michael L., Esparza, Thomas J., Stocchetti, Nino, Zipfel, Gregory J., Holtzman, David M.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577829/
https://ncbi.nlm.nih.gov/pubmed/18755980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1161591
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