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Amyloid-β Dynamics Correlate with Neurological Status in the Injured Human Brain

The amyloid-β peptide (Aβ) plays a central pathophysiological role in Alzheimer’s disease, but little is known about the concentration and dynamics of this secreted peptide in the extracellular space of the human brain. We used intracerebral microdialysis to obtain serial brain interstitial fluid (I...

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Detalhes bibliográficos
Main Authors: Brody, David L., Magnoni, Sandra, Schwetye, Kate E., Spinner, Michael L., Esparza, Thomas J., Stocchetti, Nino, Zipfel, Gregory J., Holtzman, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577829/
https://ncbi.nlm.nih.gov/pubmed/18755980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1161591
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