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Exceptionally potent inhibitors of fatty acid amide hydrolase: The enzyme responsible for degradation of endogenous oleamide and anandamide

The development of exceptionally potent inhibitors of fatty acid amide hydrolase (FAAH), the enzyme responsible for the degradation of oleamide (an endogenous sleep-inducing lipid), and anandamide (an endogenous ligand for cannabinoid receptors) is detailed. The inhibitors may serve as useful tools...

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書誌詳細
主要な著者: Boger, Dale L., Sato, Haruhiko, Lerner, Aaron E., Hedrick, Michael P., Fecik, Robert A., Miyauchi, Hiroshi, Wilkie, Gordon D., Austin, Bryce J., Patricelli, Matthew P., Cravatt, Benjamin F.
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC25778/
https://ncbi.nlm.nih.gov/pubmed/10805767
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