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Replication Licensing and Cancer - a Fatal Entanglement?

Correct regulation of the replication licensing system ensures that chromosomal DNA is precisely duplicated in each cell division cycle. Licensing proteins are inappropriately expressed at an early stage of tumorigenesis in a wide variety of cancers. Here we discuss evidence that misregulation of re...

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Bibliografski detalji
Glavni autori: Blow, J. Julian, Gillespie, Peter J.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577763/
https://ncbi.nlm.nih.gov/pubmed/18756287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2500
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