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Replication Licensing and Cancer - a Fatal Entanglement?

Correct regulation of the replication licensing system ensures that chromosomal DNA is precisely duplicated in each cell division cycle. Licensing proteins are inappropriately expressed at an early stage of tumorigenesis in a wide variety of cancers. Here we discuss evidence that misregulation of re...

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Bibliografische gegevens
Hoofdauteurs: Blow, J. Julian, Gillespie, Peter J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577763/
https://ncbi.nlm.nih.gov/pubmed/18756287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2500
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