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Replication Licensing and Cancer - a Fatal Entanglement?

Correct regulation of the replication licensing system ensures that chromosomal DNA is precisely duplicated in each cell division cycle. Licensing proteins are inappropriately expressed at an early stage of tumorigenesis in a wide variety of cancers. Here we discuss evidence that misregulation of re...

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Bibliografiska uppgifter
Huvudupphovsmän: Blow, J. Julian, Gillespie, Peter J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577763/
https://ncbi.nlm.nih.gov/pubmed/18756287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2500
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