Cyp1b1 exerts opposing effects on intestinal tumorigenesis via exogenous and endogenous substrates

Cytochrome P450 1B1 (Cyp1b1) metabolism contributes to physiological functions during embryogenesis, but also to carcinogenic activation of polycyclic aromatic hydrocarbons (PAH). We generated Cyp1b1-deficient mice carrying the Min allele of the Adenomatous polyposis coli gene. These Cyp1b1-deficien...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Halberg, Richard B., Larsen, Michele Campaigne, Elmergreen, Tammy L., Ko, Alex Y., Irving, Amy A., Clipson, Linda, Jefcoate, Colin R.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577593/
https://ncbi.nlm.nih.gov/pubmed/18794127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6750
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker