Quantitative Proteomic Identification of MAZ as a Transcriptional Regulator of Muscle-Specific Genes in Skeletal and Cardiac Myocytes

We identified a conserved sequence within the Muscle creatine kinase (MCK) promoter that is critical for high-level activity in skeletal and cardiac myocytes (MCK Promoter Element X [MPEX]). After selectively enriching for MPEX-binding factor(s) (MPEX-BFs), ICAT-based quantitative proteomics was use...

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Bibliographic Details
Main Authors: Himeda, Charis L., Ranish, Jeffrey A., Hauschka, Stephen D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577440/
https://ncbi.nlm.nih.gov/pubmed/18710939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00306-08
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