Hairpin structures formed by alpha satellite DNA of human centromeres are cleaved by human topoisomerase IIα

Although centromere function has been conserved through evolution, apparently no interspecies consensus DNA sequence exists. Instead, centromere DNA may be interconnected through the formation of certain DNA structures creating topological binding sites for centromeric proteins. DNA topoisomerase II...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jonstrup, Anette Thyssen, Thomsen, Tina, Wang, Yong, Knudsen, Birgitta R., Koch, Jørn, Andersen, Anni H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2008
Pynciau:
Nucleic Acid Enzymes
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577340/
https://ncbi.nlm.nih.gov/pubmed/18824478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn640
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