Hairpin structures formed by alpha satellite DNA of human centromeres are cleaved by human topoisomerase IIα

Although centromere function has been conserved through evolution, apparently no interspecies consensus DNA sequence exists. Instead, centromere DNA may be interconnected through the formation of certain DNA structures creating topological binding sites for centromeric proteins. DNA topoisomerase II...

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Dades bibliogràfiques
Autors principals: Jonstrup, Anette Thyssen, Thomsen, Tina, Wang, Yong, Knudsen, Birgitta R., Koch, Jørn, Andersen, Anni H.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2008
Matèries:
Nucleic Acid Enzymes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577340/
https://ncbi.nlm.nih.gov/pubmed/18824478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn640
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