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Hairpin structures formed by alpha satellite DNA of human centromeres are cleaved by human topoisomerase IIα

Although centromere function has been conserved through evolution, apparently no interspecies consensus DNA sequence exists. Instead, centromere DNA may be interconnected through the formation of certain DNA structures creating topological binding sites for centromeric proteins. DNA topoisomerase II...

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Bibliografische gegevens
Hoofdauteurs: Jonstrup, Anette Thyssen, Thomsen, Tina, Wang, Yong, Knudsen, Birgitta R., Koch, Jørn, Andersen, Anni H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577340/
https://ncbi.nlm.nih.gov/pubmed/18824478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn640
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