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Overexpression of the LexA-regulated tisAB RNA in E. coli inhibits SOS functions; implications for regulation of the SOS response

The DNA damage induced SOS response in Escherichia coli is initiated by cleavage of the LexA repressor through activation of RecA. Here we demonstrate that overexpression of the SOS-inducible tisAB gene inhibits several SOS functions in vivo. Wild-type E. coli overexpressing tisAB showed the same UV...

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Autors principals: Weel-Sneve, Ragnhild, Bjørås, Magnar, Kristiansen, Knut Ivan
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577331/
https://ncbi.nlm.nih.gov/pubmed/18832374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn633
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