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An upstream regulatory sequence stimulates expression of the perfringolysin O gene of Clostridium perfringens.

The structural gene for perfringolysin O (pfoA), a thiol-activated hemolysin of Clostridium perfringens, was cloned into Escherichia coli JM109 on a 4.6-kilobase (kb) EcoRI-NdeI fragment which contained the 1.7-kb pfoA gene and an upstream 2.9-kb region. An E. coli strain transformed by this plasmid...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Shimizu, T, Okabe, A, Minami, J, Hayashi, H
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257717/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1987025/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.1.137-142.1991
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