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High Glycolytic Flux Improves Pyruvate Production by a Metabolically Engineered Escherichia coli Strain

We report pyruvate formation in Escherichia coli strain ALS929 containing mutations in the aceEF, pfl, poxB, pps, and ldhA genes which encode, respectively, the pyruvate dehydrogenase complex, pyruvate formate lyase, pyruvate oxidase, phosphoenolpyruvate synthase, and lactate dehydrogenase. The glyc...

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Detalhes bibliográficos
Main Authors: Zhu, Yihui, Eiteman, Mark A., Altman, Ronni, Altman, Elliot
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576684/
https://ncbi.nlm.nih.gov/pubmed/18806005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01610-08
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