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Comparison of the safety and immunogenicity of delta aroC delta aroD and delta cya delta crp Salmonella typhi strains in adult volunteers.

Three attenuated Salmonella typhi strains have been constructed by introducing deletions in aroC and aroD or deletions in cya and crp into one of two wild-type parent strains, Ty2 or ISP1820. These mutant strains were designated CVD 906 (ISP1820 delta aroC delta aroD), CVD 908 (Ty2 delta aroC delta...

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Udgivet i:Infect Immun
Principais autores: Tacket, C O, Hone, D M, Curtiss, R, Kelly, S M, Losonsky, G, Guers, L, Harris, A M, Edelman, R, Levine, M M
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257661/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1730487/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.2.536-541.1992
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