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Role of gamma interferon and tumor necrosis factor alpha in resistance to Salmonella typhimurium infection.

In mice infected with a sublethal dose of Salmonella typhimurium, the injection of an anti-gamma interferon (IFN-gamma) monoclonal antibody increased bacterial proliferation in the spleen and led to death on day 7 or 8. Depletion of both CD4+ and CD8+ T cells with monoclonal antibodies in vivo had a...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Nauciel, C, Espinasse-Maes, F
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1992
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257648/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1730475/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.2.450-454.1992
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