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p8/TTDA Overexpression Enhances UV-Irradiation Resistance and Suppresses TFIIH Mutations in a Drosophila Trichothiodystrophy Model

Mutations in certain subunits of the DNA repair/transcription factor complex TFIIH are linked to the human syndromes xeroderma pigmentosum (XP), Cockayne's syndrome (CS), and trichothiodystrophy (TTD). One of these subunits, p8/TTDA, interacts with p52 and XPD and is important in maintaining TF...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Aguilar-Fuentes, Javier, Fregoso, Mariana, Herrera, Mariana, Reynaud, Enrique, Braun, Cathy, Egly, Jean Marc, Zurita, Mario
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576456/
https://ncbi.nlm.nih.gov/pubmed/19008953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000253
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