Deciphering the Energy Landscape of the Interaction Uranyl-DCP with Antibodies Using Dynamic Force Spectroscopy

Previous studies on molecular recognition of uranyl-DCP (dicarboxy-phenanthroline chelator) compound by two distinct monoclonal antibodies (Mabs U04S and U08S) clearly showed the presence of a biphasic shape in Bell-Evans' plots and an accentuated difference in slopes at the high loading rates....

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Bibliographic Details
Main Authors: Teulon, Jean-Marie, Parot, Pierre, Odorico, Michael, Pellequer, Jean-Luc
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2008
Subjects:
Biophysical Letters
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576404/
https://ncbi.nlm.nih.gov/pubmed/18790844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.141937
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