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Convulsive liability of bupropion hydrochloride metabolites in Swiss albino mice

BACKGROUND: It is known that following chronic dosing with bupropion HCl active metabolites are present in plasma at levels that are several times higher than that of the parent drug, but the possible convulsive effects of the major metabolites are not known. METHODS: We investigated the convulsive...

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書誌詳細
主要な著者: Silverstone, Peter H, Williams, Robert, McMahon, Louis, Fleming, Rosanna, Fogarty, Siobhan
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576274/
https://ncbi.nlm.nih.gov/pubmed/18922171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-859X-7-19
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