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Convulsive liability of bupropion hydrochloride metabolites in Swiss albino mice

BACKGROUND: It is known that following chronic dosing with bupropion HCl active metabolites are present in plasma at levels that are several times higher than that of the parent drug, but the possible convulsive effects of the major metabolites are not known. METHODS: We investigated the convulsive...

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Autors principals: Silverstone, Peter H, Williams, Robert, McMahon, Louis, Fleming, Rosanna, Fogarty, Siobhan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576274/
https://ncbi.nlm.nih.gov/pubmed/18922171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-859X-7-19
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