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Convulsive liability of bupropion hydrochloride metabolites in Swiss albino mice

BACKGROUND: It is known that following chronic dosing with bupropion HCl active metabolites are present in plasma at levels that are several times higher than that of the parent drug, but the possible convulsive effects of the major metabolites are not known. METHODS: We investigated the convulsive...

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Detalhes bibliográficos
Main Authors: Silverstone, Peter H, Williams, Robert, McMahon, Louis, Fleming, Rosanna, Fogarty, Siobhan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576274/
https://ncbi.nlm.nih.gov/pubmed/18922171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-859X-7-19
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