Dysregulated Information Processing by Medium Spiny Neurons in Striatum of Freely Behaving Mouse Models of Huntington's Disease

Huntington's disease (HD) is an autosomal dominant condition that compromises behavioral output. Dysfunction of medium spiny neurons (MSNs), which are the sole output system of the striatum, is thought to underlie HD pathophysiology. What is not known is how HD alters MSN information processing...

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Auteurs principaux: Miller, Benjamin R., Walker, Adam G., Shah, Anand S., Barton, Scott J., Rebec, George V.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2008
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576201/
https://ncbi.nlm.nih.gov/pubmed/18667541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.90606.2008
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