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No effect of metformin on the innate airway hyperresponsiveness and increased responses to ozone observed in obese mice

We have previously reported that obese db/db mice exhibit innate airway hyperresponsiveness. These mice also have enhanced inflammatory responses to ozone, a common air pollutant that exacerbates asthma. Since db/db mice are diabetic as well as obese, the purpose of the present study was to determin...

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Hlavní autoři: Shore, Stephanie A., Williams, Erin S., Zhu, Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576029/
https://ncbi.nlm.nih.gov/pubmed/18703763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00117.2008
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