Binding of monoclonal antibody specific for domain Ia/II of Pseudomonas aeruginosa exotoxin A at pH 4 strongly neutralizes exotoxin A-induced cytotoxicity in cell culture and in vivo.
Mouse monoclonal antibodies (MAbs) against Pseudomonas aeruginosa exotoxin A (Ex-A) were established, and 4 of 20 MAbs were extensively studied for analysis of the structure-function relationship of Ex-A. IN vivo experiments demonstrated that MAb Ex-3C7 protected mice either injected with Ex-A or in...
Zapisane w:
| Wydane w: | Infect Immun |
|---|---|
| Główni autorzy: | , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology (ASM)
1992
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257594/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1371763/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.3.1061-1068.1992 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|