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Somatostatin stimulates menin gene expression by inhibiting protein kinase A
Somatostatin is a potent inhibitor of gastrin secretion and gene expression. Menin is a 67-kDa protein product of the multiple endocrine neoplasia type 1 (MEN1) gene that when mutated leads to duodenal gastrinomas, a tumor that overproduces the hormone gastrin. These observations suggest that menin...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Physiological Society
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575917/ https://ncbi.nlm.nih.gov/pubmed/18755809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00607.2007 |
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