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Calpain activity and muscle wasting in sepsis

Muscle wasting in sepsis reflects activation of multiple proteolytic mechanisms, including lyosomal and ubiquitin-proteasome-dependent protein breakdown. Recent studies suggest that activation of the calpain system also plays an important role in sepsis-induced muscle wasting. Perhaps the most impor...

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Detalhes bibliográficos
Main Authors: Smith, Ira J., Lecker, Stewart H., Hasselgren, Per-Olof
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575901/
https://ncbi.nlm.nih.gov/pubmed/18492780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90226.2008
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