High-molecular-weight hyaluronan – a possible new treatment for sepsis-induced lung injury: a preclinical study in mechanically ventilated rats

INTRODUCTION: Mechanical ventilation with even moderate-sized tidal volumes synergistically increases lung injury in sepsis and has been associated with proinflammatory low-molecular-weight hyaluronan production. High-molecular-weight hyaluronan (HMW HA), in contrast, has been found to be anti-infla...

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Main Authors: Liu, Yung-Yang, Lee, Cheng-Hung, Dedaj, Rejmon, Zhao, Hang, Mrabat, Hicham, Sheidlin, Aviva, Syrkina, Olga, Huang, Pei-Ming, Garg, Hari G, Hales, Charles A, Quinn, Deborah A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575591/
https://ncbi.nlm.nih.gov/pubmed/18691420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc6982
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