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Purification and characterization of the lethal toxin (alpha-toxin) of Clostridium septicum.

Clostridium septicum lethal (alpha-toxin) was purified and found to be a basic protein (pI 8.4) of approximately 48 kDa that is both lethal and hemolytic. The alpha-toxin had a hemolytic activity of approximately 2 x 10(7) hemolytic units per mg and a 50% lethal dose of approximately 10 micrograms/k...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Ballard, J, Bryant, A, Stevens, D, Tweten, R K
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257555/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1541552/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.3.784-790.1992
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