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Evaluation of BRCA1 and BRCA2 mutations and risk-prediction models in a typical Asian country (Malaysia) with a relatively low incidence of breast cancer

INTRODUCTION: The cost of genetic testing and the limited knowledge about the BRCA1 and BRCA2 genes in different ethnic groups has limited its availability in medium- and low-resource countries, including Malaysia. In addition, the applicability of many risk-assessment tools, such as the Manchester...

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Detalhes bibliográficos
Main Authors: Thirthagiri, E, Lee, SY, Kang, P, Lee, DS, Toh, GT, Selamat, S, Yoon, S-Y, Taib, NA Mohd, Thong, MK, Yip, CH, Teo, SH
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575532/
https://ncbi.nlm.nih.gov/pubmed/18627636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2118
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