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Human DNA polymerase η activity and translocation is regulated by phosphorylation
Human DNA polymerase η (pol η) can replicate across UV-induced pyrimidine dimers, and defects in the gene encoding pol η result in a syndrome called xeroderma pigmentosum variant (XP-V). XP-V patients are prone to the development of cancer in sun-exposed areas, and cells derived from XP-V patients d...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575462/ https://ncbi.nlm.nih.gov/pubmed/18946034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808589105 |
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