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Dynamic stabilization of actin filaments

We report here that actin filaments in vitro exist in two populations with significantly different shrinkage rates. Newly polymerized filaments shrink rapidly, primarily from barbed ends, at 1.8/s, but as they age they switch to a stable state that shrinks slowly, primarily from pointed ends, at ≈0....

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Bibliografiske detaljer
Main Authors: Kueh, Hao Yuan, Brieher, William M., Mitchison, Timothy J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575454/
https://ncbi.nlm.nih.gov/pubmed/18931306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807394105
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