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Coronin-1A Stabilizes F-Actin by Bridging Adjacent Actin Protomers and Stapling Opposite Strands of the Actin Filament

Coronins are F-actin binding proteins that are involved, in concert with Arp2/3, Aip1 and ADF/cofilin, in rearrangements of the actin cytoskeleton. An understanding of coronin function has been hampered by the absence of any structural data on its interaction with actin. Using electron microscopy an...

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Autores principales: Galkin, Vitold E., Orlova, Albina, Brieher, William, Kueh, Hao Yuan, Mitchison, Timothy J., Egelman, Edward H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267021/
https://ncbi.nlm.nih.gov/pubmed/18177666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.12.007
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