Raft-Dependent Endocytosis of Autocrine Motility Factor/Phosphoglucose Isomerase: A Potential Drug Delivery Route for Tumor Cells

BACKGROUND: Autocrine motility factor/phosphoglucose isomerase (AMF/PGI) is the extracellular ligand for the gp78/AMFR receptor overexpressed in a variety of human cancers. We showed previously that raft-dependent internalization of AMF/PGI is elevated in metastatic MDA-435 cells, but not metastatic...

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Hauptverfasser: Kojic, Liliana D., Wiseman, Sam M., Ghaidi, Fariba, Joshi, Bharat, Nedev, Hinyu, Saragovi, H. Uri, Nabi, Ivan R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575378/
https://ncbi.nlm.nih.gov/pubmed/18974847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003597
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