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Autocrine motility factor/phosphoglucose isomerase regulates ER stress and cell death through control of ER calcium release

Autocrine motility factor/ phosphoglucose isomerase (AMF/PGI) promotes cell survival by the pAkt survival pathway. Its receptor, gp78/AMFR, is an E3 ubiquitin ligase implicated in endoplasmic reticulum (ER)-associated protein degradation. We demonstrate here that AMF/PGI also protects against thapsi...

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Detalhes bibliográficos
Main Authors: Fu, M, Li, L, Albrecht, T, Johnson, J D, Kojic, L D, Nabi, I R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131941/
https://ncbi.nlm.nih.gov/pubmed/21252914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.181
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