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Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis

TNF is a pleiotropic cytokine that activates both anti- and proapoptotic signaling pathways, with cell fate determined by the balance between these two pathways. Activation of ErbB family members, including EGF receptor (EGFR/ErbB1), promotes cell survival and regulates several signals that overlap...

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Détails bibliographiques
Auteurs principaux: Yamaoka, Toshimitsu, Yan, Fang, Cao, Hanwei, Hobbs, Stuart S., Dise, Rebecca S., Tong, Wei, Polk, D. Brent
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575333/
https://ncbi.nlm.nih.gov/pubmed/18701712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801463105
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