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Snail and Slug Promote Epithelial-Mesenchymal Transition through β-Catenin–T-Cell Factor-4-dependent Expression of Transforming Growth Factor-β3

Members of the Snail family of transcription factors have been shown to induce epithelial-mesenchymal transition (EMT), a fundamental mechanism of embryogenesis and progressive disease. Here, we show that Snail and Slug promote formation of β-catenin–T-cell factor (TCF)-4 transcription complexes tha...

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Bibliographic Details
Main Authors: Medici, Damian, Hay, Elizabeth D., Olsen, Bjorn R.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575183/
https://ncbi.nlm.nih.gov/pubmed/18799618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-05-0506
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