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Phosphatase Inhibitor-2 Balances Protein Phosphatase 1 and Aurora B Kinase for Chromosome Segregation and Cytokinesis in Human Retinal Epithelial Cells

Mitosis in Saccharomyces cerevisiae depends on IPL1 kinase, which genetically interacts with GLC8. The metazoan homologue of GLC8 is inhibitor-2 (I-2), but its function is not understood. We found endogenous and ectopic I-2 localized to the spindle, midzone, and midbody of mitotic human epithelial A...

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Главные авторы: Wang, Weiping, Stukenberg, P. Todd, Brautigan, David L.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575180/
https://ncbi.nlm.nih.gov/pubmed/18716057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-05-0460
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