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Macropinocytosis and Cytoskeleton Contribute to Dendritic Cell-mediated HIV-1 Transmission to CD4(+) T Cells

Dendritic cells (DCs) are among the first immune cells to encounter HIV-1 at the initial infection. DCs efficiently transfer HIV-1 to CD4(+) T cells via infectious or virological synapses formed between DCs and T cells. Retroviruses exploit the cytoskeletal network to facilitate viral infection and...

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Bibliografiske detaljer
Main Authors: Wang, Jian-Hua, Wells, Clive, Wu, Li
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575140/
https://ncbi.nlm.nih.gov/pubmed/18804253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.08.028
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