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Down-regulation of neurocan expression in reactive astrocytes promotes axonal regeneration and facilitates the neurorestorative effects of bone marrow stromal cells in the ischemic rat brain

The glial scar, a primarily astrocytic structure bordering the infarct tissue inhibits axonal regeneration after stroke. Neurocan, an axonal extension inhibitory molecule, is up-regulated in the scar region after stroke. Bone marrow stromal cells (BMSCs) reduce the thickness of glial scar wall and f...

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Bibliografske podrobnosti
Main Authors: Shen, Li Hong, Gao, Qi, Li, Yi, Savant-Bhonsale, Smita, Chopp, Michael
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575136/
https://ncbi.nlm.nih.gov/pubmed/18618668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20722
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