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SIMVASTATIN INHIBITS CENTRAL SYMPATHETIC OUTFLOW IN HEART FAILURE BY A NOS MECHANISM
Our previous study demonstrated that oral treatment with simvastatin (SIM) suppressed renal sympathetic nerve activity (RSNA) in the rabbits with chronic heart failure (CHF). The purpose of this experiment was to determine the effects of direct application of SIM to the central nervous system on RSN...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575087/ https://ncbi.nlm.nih.gov/pubmed/18441251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.107.136028 |
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