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Activation of Central Angiotensin Type 2 Receptors by Compound 21 Improves Arterial Baroreflex Sensitivity in Rats With Heart Failure

BACKGROUND: In a previous study we demonstrated that central administration of compound 21 (C21), a nonpeptide AT2R agonist, inhibited sympathetic tone in normal rats. In this study, we hypothesized that C21 exerts a similar effect in rats with coronary ligation–induced heart failure (HF). METHODS:...

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Detalles Bibliográficos
Publicado en:Am J Hypertens
Autores principales: Gao, Juan, Zucker, Irving H., Gao, Lie
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229732/
https://ncbi.nlm.nih.gov/pubmed/24687998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hpu044
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